Eradication programs range from application of chemical pesticides to the introduction of sterilized irradiated insect pupae (a larval stage before the adult fly emerges) to interfere with reproduction. In California fly release for eradication is done over two life cycles and success is determined when no adult flies are found eight months after application. Medfly outbreaks are estimated to have cost California $500 million (US) over the past 25 years. And the only way to conceivably block outbreaks in California has been to impose trade embargoes from countries of origin which amounts to 43 at present with 500 unique localities. It is expected that climate change will further enable Medfly spread. So a genetically modified Medfly may be just the ticket to control outbreaks.
What Oxitec has developed is a “self-limiting” Medfly. It mates with wild Meflies to suppress the insect population. In controlled netted releases done in Western Australia, compared to the sterilized irradiated technology, the Oxitec Medfly produced better results. Tests done in glassed-in greenhouses in Crete eliminated the insect pests withint 12 Netted trials in Morocco produced similar results. Now Oxitec is ready to do open field trials noting that their “self-limiting” Medfly can save agribusiness billions of dollars annually.
I have written about Oxitec before, a company spun out from Oxford University’s research laboratories focused on developing genetically modified insect technology. The company has developed “self-limiting” Aedes aegypti, the mosquito responsible for the spread of dengue, malaria and the Zika virus.
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